The Diabetes Prevention Program (DPP) was a major clinical trial, or research study, aimed at discovering whether either diet and exercise or the oral diabetes drug metformin (Glucophage) could prevent or delay the onset of type 2 diabetes in people with impaired glucose tolerance (IGT).
The answer is yes. In fact, the DPP found that over the 3 years of the study, diet and exercise sharply reduced the chances that a person with IGT would develop diabetes. Metformin also reduced risk, although less dramatically. The DPP resolved these questions so quickly that, on the advice of an external monitoring board, the program was halted a year early. The researchers published their findings in the February 7, 2002, issue of the New England Journal of Medicine.
Source Insulin Resistance - resistance to the effects of insulin produces an increase in insulin production and circulating levels (hyperinsulinemia) and can lead to skin disorders and elevated androgens (hyperandogenism). The elevated androgens like DHEAS and testosterone can lead to male pattern hair growth and acne. The androgens cause an increase in free estrogen (by reducing sex hormone binding globulin which binds both estrogens and androgens) which results in a decrease in FSH. The follicles are initially stimulated to grow but do not have enough FSH to continue to grow. This results in the polycystic appearance of the ovaries. Because follicles are not developing normally women will not ovulate normally and will not have normal menses.
Natural Ways to Become Less Insulin Resistant
Increase exercise. Exercise is proven to reduce insulin problems.
Improve your diet.
Switch from refined carbohydrates to a complex carbohydrate, low glycemic diet
High ratio of soluble fiber to insoluble fiber.
Improve quality of fat
Avoid saturated fat
Avoid trans fats
Increase monosaturated oils
Increase omega 3 oils (fish, flax).
Smaller, more frequent meals.
Reduce alcohol intake.
Have mixed meals of carbohydrate, protein and fat.
A number of nutritional supplements may improve Syndrome X:
Glucomannan (soluble fiber)
NAC (N-acetyl cysteine)
The mineral standout among these may be chromium in the form of chromium picolinate. Chromium is so effective at reversing insulin resistance that one 1997 study found that 1,000 mcg of chromium picolinate daily reduced blood sugar and insulin levels in type 2 diabetics to near normal after four months-something that medications could not achieve (Diabetes, 1997, vol. 46). In various other studies, chromium also has been found to help normalize the individual components of Syndrome X.
And in daily dosages of 200 to 400 mcg, it helps those with reactive hypoglycemia (blood sugar highs followed by blood sugar lows). So, chromium acts as a blood sugar regulator. However, those who take sugar-lowering drugs should take note: Supplemental chromium works so well at improving insulin function that less medication is usually needed. Sometimes, medication can be eliminated completely over time. This is a good thing-it indicates a reversal or lessening of insulin resistance-but it also means that your customers should work with their doctors to carefully monitor their condition and avoid overmedicating themselves.
Chromium isn't the only supplement that helps reduce the high blood sugar levels that can occur with Syndrome X. Herbalists have long used various herbs, including ginseng, fenugreek, bitter melon and gymnema sylvestre, to lower blood sugar levels and research is slowly but surely confirming that these herbs do have blood-sugar-lowering properties. In one study out of the University of Toronto, healthy subjects who were given American ginseng (Panax quinquefolius) had a 26 to 38 percent reduction in blood sugar levels, while diabetics who took the herb had a 20 percent reduction (Archives of Internal Medicine, 2000, vol. 160).
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